NPR interviewed Paul Reubens recently on their Fresh Air program. Here's their summary:
The complete 45-episode series of the TV show Pee-Wee's Playhouse is now out on DVD. Reubens originally created the Pee-Wee character at the Los Angeles improv group called The Groundlings. Pee-Wee's Playhouse went on the air in 1986. It ran on CBS for 5 years, garnering 22 Emmys.
Even though it's NPR there's still a KS or two.